A suspect had been taken into custody after police officers in New York City responded on Tuesday afternoon to reports of a shooting or vehicle collision in Lower Manhattan, the authorities said.

Initial reports said a van on the bike path had run down several people. At one point shots may have been fired, but it was not clear who had fired them. A law enforcement official said there were reports that several people were dead.

A video posted to social media showed bodies and bicycles on a bicycle path near Chambers and West Streets by Stuyvesant High School. Some people were being treated for injuries near a mangled school bus.

Police officers, including the bomb squad, responded to the scene and several nearby buildings, including Stuyvesant, were placed on lockdown, with those inside told to take shelter.

The Fire Department said officials responded just after 3 p.m. to reports of a mass casualty at Chambers and West Streets.

The police said around 3:30 p.m. that they were not looking for additional suspects.

Reports on Twitter indicated that people heard gunfire and a witness said that a school bus had been damaged.

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